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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Antibiot (Tokyo). 2013 Dec 4;67(1):89–97. doi: 10.1038/ja.2013.125

Figure 2.

Figure 2

Sequence similarity relationships among PKSs involved in the biosynthesis of known polyketide natural products. The amino-acid sequences of 62 representative assembly-line PKSs and PKS–NRPSs, plus the three orphan PKSs highlighted in this report, were compared in a pairwise manner using a gene-cluster similarity score. Scale bar displays the distance between gene clusters (between 0 and 1). The label for each PKS lists the Genbank ID and cluster number, date the sequence was deposited in NCBI, number of KS, AT, C and A domains, and sequence origin as listed in NCBI. The three orphans highlighted in the text are displayed in red. A full color version of this figure is available at The Journal of Antibiotics journal online.