Table 4.
WGA analysis results for SNPs in ADIPOQ in NWE population
| SNPs | Start position | MAF |
P value
|
|||
|---|---|---|---|---|---|---|
| Pooled population (n = 1845) | Cases (n = 921) | Controls (n = 924) | ||||
|
| ||||||
| Adjusted for
| ||||||
| Age, sex, site | Age, sex, site, ADL | Age, sex, site | Age, sex, site | |||
| rs864265a | 188,036,986 | T: 0.14 | 0.058 | 0.022 | 0.032 | 0.213 |
| rs182052 | 188,043,476 | A: 0.37 | 0.137 | 0.145 | 0.352 | 0.345 |
| rs16861205 | 188,044,328 | A: 0.09 | 0.607 | 0.573 | 0.721 | 0.331 |
| rs17366568 | 188,053,147 | A: 0.13 | 3.2E–06 | 3.70E–06 | 0.002 | 3.50E–04 |
| rs2241767 | 188,053,890 | G: 0.11 | 0.392 | 0.412 | 0.198 | 0.918 |
| rs3821799 | 188,054,180 | T: 0.40 | 0.015 | 0.026 | 0.037 | 0.500 |
| rs3774261 | 188,054,253 | A: 0.38 | 3.44E–08 | 5.15E–08 | 6.76E–06 | 0.004 |
| rs6444174b | 188,055,883 | C: 0.005 | – | – | – | – |
| rs6773957 | 188,056,399 | A: 0.38 | 3.02E–08 | 4.78E–08 | 8.72E–06 | 0.003 |
| rs11712615a | 188,092,833 | G: 0.30 | 0.958 | 0.932 | 0.484 | 0.46 |
MAF, minor allele frequency; NWE, Northern and Western European; SNP, single-nucleotide polymorphism; WGA, whole genome association.
a
SNPs on the Affymetrix 500k chip that flank ADIPOQ.
b
SNP excluded from analysis in Plink as MAF <0.01.