Table 1.
Statistic analyses of 27 recorded variables of collected data (N = 348)
Variables | Ventilator Weaning | Significance (p-value) | |
---|---|---|---|
Successful (n = 159) |
Failed (n = 189) |
||
Demographic Data | |||
Gender (male/female) | 90/69 | 110/79 | 0.828 |
Age*** | 72.67 ± 14.95 | 78.04 ± 12.22 | <0.001 |
Physiology and Disease Factors | |||
APACHE II score at hospitalization* | 17.21 ± 4.94 | 18.62 ± 5.83 | 0.017 |
Coma Scale at hospitalization | 9.54 ± 3.37 | 9.34 ± 3.93 | 0.611 |
Albumin (mg/dl) | 2.78 ± 0.48 | 2.86 ± 2.77 | 0.725 |
Blood urea nitrogen (BUN) (mg/dl) *** | 25.95 ± 17.45 | 39.26 ± 29.77 | <0.001 |
Creatinine (mg/dl) | 1.25 ± 0.92 | 3.97 ± 20.51 | 0.095 |
Hemoglobin (g/dl) | 10.92 ± 1.61 | 10.46 ± 5.52 | 0.311 |
Pulmonary disease | 92 (57.9%) | 101 (53.4%) | 0.449 |
Cardiac disease | 26 (16.4%) | 36 (19.0%) | 0.575 |
Historical respiratory disease‡ | 32 (20.1%) | 70 (37.0%) | 0.001 |
Brain vessel disease | 18 (11.3%) | 14 (7.4%) | 0.264 |
Other causes related to int. medicine‡ | 80 (50.3%) | 129 (68.3%) | 0.001 |
Acute respiratory distress syndrome | 3 (1.9%) | 0 (0%) | 0.094 |
Multiple-organ failure† | 0 (0%) | 8 (4.2%) | 0.009 |
Trauma | 0 (0%) | 4 (2.1%) | 0.128 |
Brain Surgery‡ | 41 (25.8%) | 19 (31.7%) | <0.001 |
Other kinds of surgeries† | 8 (5.0%) | 24 (12.7%) | 0.015 |
Care and Treatment Factors | |||
Tracheotomy | 75 (47.2%) | 71 (37.6%) | 0.081 |
Coma scale at weaning*** | 9.23 ± 2.94 | 7.37 ± 2.96 | <0.001 |
RSBI at weaning*** | 91.59 ± 41.94 | 162.58 ± 79.62 | <0.001 |
Length of ICU admission (day)* | 16.72 ± 6.54 | 18.26 ± 6.35 | 0.026 |
Days using ventilator*** | 33.38 ± 12.01 | 41.24 ± 16.68 | <0.001 |
Ventilator associated pneumonia‡ | 20 (12.6%) | 77 (40.7%) | <0.001 |
Blood stream infection‡ | 0 (0%) | 8(4.2%) | 0.009 |
Urinary tract infection‡ | 19 (11.9%) | 50 (26.5%) | 0.001 |
Nosocomial infection | 8 (5.0%) | 10 (5.3%) | 1.000 |
Note: *p<0.05, ** p<0.01, and ***p<0.001 with Student's t-test; †p<0.05 and ‡p<0.01 with Pearson χ2 test.