Table 1.
CYP2D6 Alleles Analyzed in This Study.
| Allele | SNP | Change | Metabolic activity | Classification |
|---|---|---|---|---|
| *1 | Reference allele | Normal | Extensive metabolizer | |
| *2 | rs16497 | 1661G>C; 4180G>C | Normal | Extensive metabolizer |
| *3 | rs3574268 | 2549delA | None | Poor metabolizer |
| *4 | rs3892097 | 1846G>A | None | Poor metabolizer |
| *5 | Whole gene deletion | None | Poor metabolizer | |
| *9 | rs5030656 | 2615-2617del AAG | Decreased | Intermediate metabolizer |
| *10 | rs1065852 | 100C>T and the absence of 1846G>A | Decreased | Intermediate metabolizer |
| *17 | rs28371706 | 1023C>T | Decreased | Intermediate metabolizer |
| *39 | rs1135840 | 1661G>C | Normal | Extensive metabolizer |
Note. SNP = single-nucleotide polymorphism.