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. Author manuscript; available in PMC: 2014 May 21.
Published in final edited form as: Biol Res Nurs. 2012 Jun 20;15(4):382–389. doi: 10.1177/1099800412449181

Table 4.

Multivariate Binary Logistic Regression for Postoperative Nausea and Vomiting (PONV).

Variable Odds ratio (OR) 95% Confidence intervals for OR
p value
Lower Upper
History of PONV 5.379 1.574 18.387 .007
Gender 0.236 .084 .662 .006
Smoking status 1.359 .552 3.343 .505
Total opioidsa 0.073 .005 1.046 .054
CYP2D6 phenotype
 EM (REF) 1.00
 IM 0.492 .010 24.171 .721
 PM 0.026 .002 .288 .003
 Age 0.966 .931 1.003 .071
CYP2D6 phenotype by total opioids
 EM 1.00 .036
 IM 4.616 .026 822.837 .563
 PM 207.726 3.525 12240.88 .010

Note. EM = extensive metabolizers; IM = intermediate metabolizers; PM = poor metabolizers.

a

Adjusted by weight.