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. 2013 Oct 25;13:154. doi: 10.1186/1471-230X-13-154

Table 4.

Tumor board review of H&N cancer patients with modified treatment strategy after IEE screening

No. H&N cancer / TNM stage Location / size (cm) / pathology (TNM stage) of esophagus Treatment strategy without IEE screening Treatment strategy with IEE screening
1
Oropharynx / II
Lower third / 0.3 / LGIN
Tumor excision
Tumor excision + EMR of esophageal lesion
2
Hypopharynx / I
Middle third / 0.5 / LGIN
Tumor excision
Tumor excision + EMR of esophageal lesion
3
Oropharynx / III
Lower third / 0.5 / LGIN
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + EMR of esophageal lesion + Adjuvant CCRT
4
Hypopharynx / III
Middle third / 6.0 / SCC (IIA)
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + Adjuvant CCRT with RT field involving esophagus
5
Larynx / I
Middle / 1.5 / HGIN
Laryngectomy
Laryngectomy + ESD of esophageal lesion
6
Larynx / I
Upper / 6.0 / SCC (IB)
Laryngectomy
Laryngectomy + Esophagectomy + Adjuvant CCRT
7
Oropharynx / IVA
Upper / 0.6 / SCC (IA)
Neoadjuvant CCRT + Tumor excision + LN dissection
Neoadjuvant CCRT + Tumor excision + Esophagectomy
8
Oropharynx / II
Middle / 4.0 / SCC (IA)
Tumor excision + Adjuvant CCRT
Tumor excision + Esophagectomy + Adjuvant CCRT
9
Hypopharynx/IVA
Middle / 2.0 / HGIN
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + LN dissection + RFA of esophageal lesion + Adjuvant CCRT
10
Hypopharynx / IVB
Upper / 1.5 / SCC(IB)
Definitive CCRT
Definitive CCRT with RT field involving the esophagus
11
Hypopharynx/III
Middle / 5.0 / SCC (IIIA)
Tumor excision + LN dissection + Adjuvant CCRT
Neoadjuvant CCRT + Tumor excision + LN dissection + Esophagectomy
12
Hypopharynx / IVB
Middle / 1.5 / SCC (IIIA)
Definitive CCRT
Definitive CCRT with RT filed involving the esophagus
13
Oral cavity / II
Lower / 0.2 / LGIN
Tumor excision
Tumor excision + EMR of esophageal lesion
14
Hypopharynx / III
Middle / 0.8 / HGIN
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + LN dissection + ESD of esophageal lesion + Adjuvant CCRT
15
Oral cavity / I
Upper / 2.0 / SCC ( IB)
Tumor excision
Tumor excision + Esophagectomy
16
Oral cavity / II
Middle / 1.0 / SCC (IA)
Tumor excision
Tumor excision + EMR of esophageal lesion
17
Oral cavity / IVB
Middle / 2.0 / SCC (IIIA)
Definitive CCRT
Definitive CCRT with RT field involving esophagus
18
Hypopharynx / IVA
Upper / 2.0 / SCC (IB)
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + LN dissection + Adjuvant CCRT with RT field involving esophagus
19
Hypopharynx / IVA
Middle / 0.8 / HGIN
Tumor excision + LN dissection + Adjuvant CCRT
Tumor excision + LN dissection + EMR + Adjuvant CCRT
20 Larynx / IVA Middle / 6.0 / SCC (IB) Laryngectomy + Adjuvant CCRT Laryngectomy + Esophagectomy + Adjuvant CCRT

Abbreviation: CCRT concurrent chemoradiotherapy, EMR endoscopic mucosal resection, ESD endoscopic submucosal dissection, H&N head and neck, HGIN high-grade intraepithelial neoplasia, IEE image-enhanced endoscopy, LN lymph node, LGIN low-grade intraepithelial neoplasia, RFA radiofrequency ablation, SCC squamous cell carcinoma.

HHS Vulnerability Disclosure