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. 2013 Oct 7;34(12):1650–1661. doi: 10.1002/humu.22433

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© 2013 The Authors. *Human Mutation published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Characterization of t(5;19)(p15.3;q13.1) breakpoints and identification of an intragenic deletion of UBE2QL1 in a t(5;19)(p15.3;q13.1) associated renal tumor. A: Sequence of der(5) breakpoint. B: Sequence of der(19) breakpoint. There are four bases, CCTG, for which it was not possible to ascribe their chromosomal origin. C: Multiplex ligation-dependent probe amplification bar chart showing deviation of UBE2QL1 probes from reference probes for exons 1 and 2 in a t(5;19)(p15.3;q13.1) associated renal oncocytoma. There is a significant deviation for exon 1 probes indicating a deletion of exon 1 (unpaired t-test, error bars = SEM, ^**P < 0.01).