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. 2014 Feb 3;30(11):1569–1578. doi: 10.1093/bioinformatics/btu021

Table 1.

Metabolic models used in the presented study

Organism Model Reactions/ Metabolites EFMs
Saccharomyces cerevisiae YEAST1a 78/62 1 515 315d
S. cerevisiae YEAST2a 83/63 68 868 602d
Escherichia coli ECOLIb 95/94 226 269 020d
P. tricornutum DIATOMc 318/335 1 934 729 551e

aJevremović and Boley, 2012. bJungreuthmayer et al., 2013. cThis work. dEFMs validated by comparing split and unsplit network results. eFourteen reactions used for iterative splitting. Some subnetworks were recalculated varying the number of reactions for splitting to validate results.