Table 1.
The average number of significant gene sets identified by INT and MPMWS at different heterogeneity levels
Significant gene set | Both INT and MPMWS |
INT only |
MPMWS only |
||||||
---|---|---|---|---|---|---|---|---|---|
γ values (%) | Positive | TP | TP (%) | Positive | TP | TP (%) | Positive | TP | TP (%) |
100 | 7.33 | 6.92 | 94.41 | 8.52 | 1.08 | 12.68 | 9.04 | 1.37 | 15.15 |
90 | 6.59 | 6.17 | 93.63 | 8.75 | 1.13 | 12.91 | 9.51 | 1.72 | 18.09 |
80 | 5.79 | 5.36 | 92.57 | 9.09 | 1.24 | 13.64 | 9.94 | 2.05 | 20.62 |
60 | 3.61 | 3.14 | 86.98 | 9.54 | 1.28 | 13.42 | 11.06 | 2.86 | 25.86 |
40 | 1.7 | 1.17 | 68.82 | 9.78 | 1.04 | 10.63 | 11.5 | 2.96 | 25.74 |
20 | 0.76 | 0.19 | 25.00 | 9.72 | 0.63 | 6.48 | 10.66 | 1.77 | 16.60 |
Ten of 207 gene sets were selected as causal, and the results were averaged over 300 repeats.