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. Author manuscript; available in PMC: 2014 May 21.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2014 Feb 27;100(4):250–259. doi: 10.1002/bdra.23228

FIGURE 1.

FIGURE 1

Genotype phenotype correspondence in FGFR-related craniosynostosis syndromes. A: Placement of the syndromic cases and unaffected individuals on PC1 and PC2 in the shape space (principal components analysis of the Procrustes shape coordinates) when analyzing all landmarks and semilandmarks measured on the facial skeleton. B: Shape changes associated with PC1 when analyzing the facial skeleton. The warped facial skeleton in red corresponds to the facial shape of the FGFR2S252W group while the warped facial skeleton in gray corresponds to the facial shape of the unaffected individuals.