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. 2014 Jul 21;353(100):67–77. doi: 10.1016/j.jtbi.2014.03.015

Fig. 10.

Fig. 10

Gene regulatory networks which yield bistability. (A) Mutual negative regulation between X and Y drives differentiation of a cell to express either X or Y, with the indirect repression of X by Y (via Z) being dispensible. (B) An alternative network, where the indirect repression of X by Y (via Z) is necessary to drive differentiation of a cell to express Y.