Table 4.

Bivariate analysis of pathologic features and immunoexpression of biomarkers in papillary RCC ^a,^b

	T stage c	Fuhrman grade c	Tumor size d
PTEN	.54	.23	.77
phos-AKT	.30	.99	.64
phos-S6	.59	.99	.43
4EBP1	.27	.33	.80
c-MYC	.99	.35	.12
p27	.70	.35	.53
HIF-1α	.03	.65	.01

^aBiomarkers categorized as positive vs negative using an H score higher than 0 as the threshold for all biomarkers, except for PTEN. Immunoexpression of PTEN was categorizes as “PTEN loss” vs “no PTEN loss” using an H score of 10 or lower for PTEN loss.

^bSignificance level was adjusted to α = .02 using Šidák correction.

^cValues provided correspond to P values estimated using the Fisher exact test.

^dValues provided correspond to P values estimated using the Mann-Whitney U test.