Table 1.
MIC values of antimicrobials for E.coli isolates carrying blaNDM-1 and their transformants
|
Antimicrobials |
MIC values (μg/ml) |
||||
|---|---|---|---|---|---|
| E. coli WZ33 | a E.coli DH5α (WZ33) | E.coli WZ51 | a E. coli DH5α (WZ51) | E. coli DH5α | |
| ampicillin |
>256 |
>256 |
>256 |
>256 |
1.5 |
| piperacillin/tazobatam |
>256 |
16 |
>256 |
256 |
0.75 |
| piperacillin |
>256 |
16 |
256 |
>256 |
0.038 |
| ceftazidime |
>256 |
>256 |
>256 |
>256 |
0.094 |
| cefotaxime |
>256 |
64 |
>256 |
192 |
0.047 |
| cefepime |
>256 |
16 |
>256 |
4 |
0.047 |
| aztreonam |
32 |
0. 023 |
>256 |
12 |
0.023 |
| cefoxitin |
>256 |
>256 |
>256 |
>256 |
0.75 |
| imipenem |
8 |
6 |
24 |
12 |
0.094 |
| meropenem |
>32 |
6 |
>32 |
3 |
0.016 |
| ertapenem |
>32 |
24 |
>32 |
4 |
0.008 |
| amikacin |
1.5 |
0.75 |
2 |
0.50 |
0.50 |
| gentamicin |
24 |
0.38 |
16 |
0.125 |
0.125 |
| levofloxacin |
24 |
0.047 |
≥32 |
0.016 |
0.023 |
| trimethoprim/sulfamethoxazole |
0.75 |
0.008 |
>32 |
0.008 |
0.008 |
| polymyxin B |
1.5 |
0.38 |
1.5 |
0.38 |
0.38 |
| tigecycline |
0.19 |
0.5 |
1 |
0.19 |
0.19 |
| Fosfomycin | 0.5 | 0.25 | 2 | 0.94 | 0.94 |
a, transformant.