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. 2014 Apr 11;2:43. doi: 10.1186/2051-5960-2-43

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Copyright © 2014 Wacker et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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KW1 expression reduces the viability of different Aβ(1–40) expressing fly lines. (A-C) Lifespan measurements of Aβ40 flies (filled) and KW1;Aβ40 flies (unfilled) (A), Aβ40-51D flies (filled) and KW1;Aβ40-51D flies (unfilled) (B) and Aβ40-29.1 flies (filled) and KW1;Aβ40-29.1 flies (unfilled) (C). (D) Fly viability versus Aβ concentration in the fly head. The fly viability (%) is given relative to fly lines without KW1 expression. Symbols: Filled diamond: KW1 relative to WT. Unfilled square: KW1;Aβ40-29.1 relative to Ab40-29.1. Unfilled triangle: KW1;Aβ40-51D relative to Aβ40-51D. Unfilled circle: KW1;Aβ40 relative to Aβ40. Data were fitted by linear regression (R = 0.86). For original values please refer to Table 1.