Table 4.
HRs and 95% CIs for the association between alcohol use disorders and Parkinson’s disease distributed by age of first admission with Parkinson’s disease in the Swedish National Inpatient Register 1972-2008, n = 602,930
| |
Total population |
≤44 |
45-59 |
60-74 |
≥75 |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | n | HR a | (95% CI) | p-value b | n | HR a | (95% CI) | p-value b | n | HR a | (95% CI) | p-value b | n | HR a | (95% CI) | p-value b | |
| Appendicitis ref |
326,403 |
10 |
1 |
|
|
53 |
1 |
|
|
226 |
1 |
|
|
369 |
1 |
|
|
| Alcohol model 1c |
276,527 |
14 |
2.71 |
(1.20–6.10) |
0.016 |
119 |
3.58 |
(2.59–4.94) |
0.0001 |
559 |
3.78 |
(3.24–4.41) |
<.0001 |
391 |
1.67 |
(1.45–1.93) |
<.0001 |
| Model 2 |
|
|
2.41 |
(0.98–5.90) |
0.056 |
|
1.94 |
(1.38–2.72) |
<.0001 |
|
2.00 |
(1.71–2.34) |
<.0001 |
|
1.03 |
(0.89–1.18) |
0.732 |
| Model 3 |
|
|
2.69 |
(1.17–6.12) |
0.020 |
|
3.37 |
(2.42–4.69) |
<.0001 |
|
3.55 |
(3.03–4.16) |
<.0001 |
|
1.60 |
(1.38–1.85) |
<.0001 |
| Model 4 | 2.39 | (0.96–5.93) | 0.060 | 1.84 | (1.30–2.60) | 0.0006 | 1.84 | (1.58–2.18) | <.0001 | 0.91 | (0.78–1.06) | 0.226 | |||||
aAbbreviations: HRs, hazard ratios.
bTested with 95% significant level.
cModel 1 crude.
Model 2 adjusted for age at exposure.
Model 3 adjusted for sex.
Model 4 adjusted for age at exposure and sex.