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. Author manuscript; available in PMC: 2014 May 21.
Published in final edited form as: Neurosci Lett. 2008 Dec 24;451(2):114–118. doi: 10.1016/j.neulet.2008.12.022

Figure 2.

Figure 2

OLs from 16 day normal and jimpy (Jp) corpus callosum double-labeled for APC and either KOP (A–F) or MOP (G–L) and counterstained with Hoechst 33342. Many normal, APC+ OLs express KOP robustly (arrows indicate double-labeled cells in panels A–C). There is little KOP staining in jimpy corpus callosum (D–F). Although APC+ OLs are present (arrows in D), most are not KOP+ (E). The inset in F shows an APC+, KOP+ jimpy OL to illustrate morphology. In contrast, there is robust expression of MOP in APC+ OLs in both normal (G–I) and Jp (J–L) corpus callosum. Arrows in G–I indicate double-labeled cells in wild-type. Arrows in J–L indicate double-labeled cells in jimpy.