Table 3.
Cell wall synthesis-related genes that were differentially expressed in the airSR mutant compared to the NCTC8325 wild-type
| Gene | Product | ΔairSR/WT ratio a | |
|---|---|---|---|
| SAOUHSC_00114 |
cap5A |
Capsular polysaccharide biosynthesis protein, putative |
−3.61 |
| SAOUHSC_00115 |
cap5B |
Capsular polysaccharide synthesis enzyme Cap5B |
−2.86 |
| SAOUHSC_00116 |
cap8C |
Capsular polysaccharide synthesis enzyme Cap8C |
−2.91 |
| SAOUHSC_00117 |
cap5D |
Capsular polysaccharide biosynthesis protein Cap5D |
−2.4 |
| SAOUHSC_00119 |
cap8F |
Capsular polysaccharide synthesis enzyme Cap8F |
−2.34 |
| SAOUHSC_00122 |
cap5I |
Capsular polysaccharide biosynthesis protein Cap5I |
−2.1 |
| SAOUHSC_00124 |
cap5K |
Capsular polysaccharide biosynthesis protein Cap5K |
−2.18 |
| SAOUHSC_00126 |
cap8M |
Capsular polysaccharide biosynthesis protein Cap8M |
−2.02 |
| SAOUHSC_00127 |
cap5N |
Cap5N protein/UDP-glucose 4-epimerase, putative |
−2.14 |
| SAOUHSC_00222 |
tagB |
TagB protein, putative |
2.24 |
| SAOUHSC_00295 |
nanA |
N-acetylneuraminate lyase |
−2.02 |
| SAOUHSC_00469 |
spoVG |
Regulatory protein SpoVG |
−2.51 |
| SAOUHSC_00545 |
sdrD |
sdrD protein, putative |
−3.68 |
| SAOUHSC_00640 |
tagA |
Teichoic acid biosynthesis protein |
−2.08 |
| SAOUHSC_00812 |
clfA |
Clumping factor, ClfA |
−4.72 |
| SAOUHSC_00918 |
|
Truncated MHC class II analog protein |
2.15 |
| SAOUHSC_00953 |
|
Diacylglycerol glucosyltransferase |
−2.21 |
| SAOUHSC_00974 |
|
Glycosyl transferase, group 1 |
4.24 |
| SAOUHSC_01106 |
murI |
Glutamate racemase, MurI |
−2.12 |
| SAOUHSC_01145 |
pbp1 |
Penicillin-binding protein 1 |
−2.05 |
| SAOUHSC_01147 |
murD |
UDP-N-acetylmuramoylalanine--D-glutamate ligase, MurD |
−2.58 |
| SAOUHSC_01148 |
ftsQ |
Cell division protein, putative |
−2.38 |
| SAOUHSC_01346 |
|
Glycine betaine transporter, putative |
4.62 |
| SAOUHSC_01400 |
|
Alanine racemase, putative |
−2.81 |
| SAOUHSC_02317 |
murF |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase |
−2.3 |
| SAOUHSC_02318 |
ddl |
D-alanyl-alanine synthetase A |
−2.34 |
| SAOUHSC_02399 |
glmS |
Glucosamine--fructose-6-phosphate aminotransferase |
−2.05 |
| SAOUHSC_02444 |
|
Osmoprotectant transporter, BCCT family, opuD-like protein |
−2.86 |
| SAOUHSC_02998 | cap5C | Capsular polysaccharide biosynthesis protein, Cap5C | 2.04 |
a “-” indicates down-regulated in the airSR mutant.