Table 2.
Comparisons of the treatment (Black cohosh) and control (placebo) groups in terms of the Greene climacteric scale total and subscale scores at baseline and two follow-up time-points
|
Outcome variables |
Treatment (n = 42) Mean ± SD |
Control (n = 42) Mean ± SD |
Comparison of the groups |
||
|---|---|---|---|---|---|
| Adjusted MD (95%CI) | P | Partial Eta 2 | |||
|
Total score (0–63) |
|
|
|
|
|
| Baseline |
33.8 ± 6.4 |
31.1 ± 6.3 |
2.7 (-0.1 to 5.4) |
0.059 |
|
| 4 weeks |
16.7 ± 7.7 |
22.9 ± 9.2 |
-7.8 (-11.1 to -4.4) |
< 0.001 |
0.21 |
| 8 weeks |
8.0 ± 5.5 |
19.5 ± 11.0 |
-12.9 (-16.2 to -9.3) |
< 0.001 |
0.39 |
|
Vasomotor symptoms (0–6) |
|
|
|
|
|
| Baseline |
4.0 ± 1.7 |
3.5 ± 1.6 |
0.5 (-2.9 to 1.2) |
0.22 |
|
| 4 weeks |
1.8 ± 2.0 |
2.6 ± 1.7 |
-1.1 (-0.4 to -1.8) |
0.002 |
0.11 |
| 8 weeks |
0.7 ± 1.6 |
2.4 ± 1.8 |
-1.9 (-1.2 to -2.6) |
< 0.001 |
0.26 |
|
Psychiatric symptoms (0–33) |
|
|
|
|
|
| Baseline |
18.8 ± 4.8 |
18.8 ± 4.3 |
0.1 (-2.1 to 1.9) |
0.92 |
|
| 4 weeks |
10.8 ± 5.0 |
13.3 ± 6.4 |
-2.6 (-0.3 to -4.9) |
< 0.001 |
0.16 |
| 8 weeks |
4.2 ± 3.5 |
11.4 ± 7.4 |
-7.3 (-9.6 to -5.0) |
< 0.001 |
0.31 |
|
Physical symptoms (0–21) |
|
|
|
|
|
| Baseline |
7.7 ± 3.5 |
6.6 ± 2.7 |
1.1 (-0.3 to 2,5) |
0.10 |
|
| 4 weeks |
3.1 ± 2.3 |
4.7 ± 2.8 |
-2.0 (-3.1 to -1.0) |
< 0.001 |
0.06 |
| 8 weeks |
1.4 ± 1.5 |
3.7 ± 2.4 |
-2.5 (-3.3 to -1.7) |
< 0.001 |
0.33 |
|
Loss of interest in sex (0–3) |
|
|
|
|
|
| Baseline |
2.6 ± 0.8 |
2.4 ± 1.4 |
0.2 (-0.7 to 0.3) |
0.47 |
|
| 4 weeks |
1.8 ± 1.0 |
1.9 ± 1.0 |
-0.37 (-0.72 to -0.03) |
0.03 |
0.06 |
| 8 weeks | 1.6 ± 1.1 | 1.9 ± 1.0 | -0.52 (-0.89 to -0.15) | 0.006 | 0.09 |