Figure 2. Trophoblast cells prevent inflammatory cytokine release by CD14+ cells under PAMP stimulation.

Maternal monocytes were co-cultured or not with Swan-71 cells in the absence or presence of LPS (10 µg/ml), PGN (10 µg/ml), or poly [I:C] (10 µg/ml). After 24 hours supernatants were collected to quantify TNF-α (A) and IL-1β (B) by ELISA. Results are expressed as mean ± SEM pg/ml from 3 independent experiments (*p<0.05 Wilcoxon test).