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Effects of local heart irradiation on mitophagy mediators and mitochondrial mass. Panel A: Representative immunoblot showing protein levels of mitophagy mediators in mitochondrial lysates at 6 months after sham-irradiation (lanes 1–4) or irradiation (lanes 5–9). Data of all time points are shown in Table 2. Panel B: The mitochondrial isolation resulted in a larger mass of mitochondria from irradiated hearts. Average ± sem, n = 4–5. *P < 0.05 when compared to sham-irradiated control.
