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. 2014 May 21;9(5):e97655. doi: 10.1371/journal.pone.0097655

Figure 3. Evaluation of time-frame of BBB permeabilization by K16ApoE and retention-time of EB in the brain delivered by K16ApoE.

Figure 3

A- Stains of EB from brain specimens from mice in which K16ApoE was injected first and then EB was injected 5 min, 10 min, 30 min, 1 h, 2 h and 4 h after. Cardiac perfusion was done 1 h after injection of the dye followed by collection of brains. B - Stains of EB from brain specimens from mice in which K16ApoE was injected first and then EB was injected 10 min after. Perfusion was done at indicated times followed by collection of brains.