Table 3. Diagnostic value of examined cytokines to discriminate pancreatic cancer from non-cancerous states in humans.

Parameter	IL-6	IL-8	IL-10	IL-23	TNFα
Indication of	Cancer	cancer	cancer	other malignancies	cancer
Area under ROC curve	0.82; p<0.0002	0.71; p<0.01	0.82; p<0.0001	0.65; p<0.04	0.74; p<0.005
Suggested cut-off value	≥4,92 pg/mL	≥51,15 pg/mL	≥7,35 pg/mL	≥32,5 pg/mL	≥6,75 pg/mL
Sensitivity [%]	86.0	72.1	72.1	34.9	76.7
Specificity [%]	56.6	71.7	81.8	94.9	60.6
Positive predictive value [%]	46.3	52.5	63.3	75.0	45.8
Negative predictive value [%]	90.3	85.5	87.1	77.0	85.7

IL – interleukin TNFα – tumor necrosis factor alpha.

ROC – receiver operating characteristics p – level of significance.