Table 1.

Overview of the protein information used in this work.

	Human	Yeast	E. coli
Reviewed proteins in Uniprot	20226	6619	4303
PDB chain IDs mapped to reviewed Uniprot entries	41605	7585	15661
Proteins with at least one mapped PDB chain ID	4519	920	1223
Proteins with at least one GO annotation	18283	5908	3744