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. 2014 May 21;9(5):e97565. doi: 10.1371/journal.pone.0097565

Figure 1. Effect of fetuin-A or albumin on CaP-induced VSMC death.

Figure 1

VSMCs in 96-well plates were exposed to either control serum-free medium (no additions) or CaP particles (CaP, 25 µg/mL) in serum-free medium with or without different concentrations of fetuin-A (A) or albumin (B) for 1 hour. Both fetuin-A and albumin inhibited CaP-particle-induced VSMC death in a concentration-dependent manner, as measured by PI uptake (fluorescence intensity with blanks subtracted, n = 4, means ± S.D, *P<0.01, **P<0.0001, ***P<0.00001.).