Table 2.

Key attributes of the ELLIPTA DPI: selected quotations from participants with asthma (N = 33) and COPD (N = 42)

Relevant emergent themes (no. of COPD/asthma patients reporting)	Relevant quotations to illustrate theme, COPD patients	Relevant quotations to illustrate theme, asthma patients
Ease of use
Ease and simplicity (16/17)	“Life made less complicated”	“It’s straight-forward in its use”
	“Very easy”	“You really don’t have to think about it, it’s that easy”
	“Extremely easy to use”	“It a no brainer in how to use”
Simple/Intuitive (9/5)	“It’s simple and takes the frustration out of it”	“It has a very simple design”
	“It’s easy to learn to use”	“It is really well thought out”
		“Really don’t need instructions to use the device, it’s very intuitive.”
	“You don’t need to be a rocket scientist to use the device, it’s really very simple”
Simple steps (8/3)	“Just flip open the cover and inhale”	“Open and inhale”
	“One hand, one shot, no thought.”	“Pull back the lever and inhale”
Issues with Lever Action (2/5)	“Opening is a little difficult, the cover feels tight when I go to slide”	“Lever drags when I pinch it to slide it open”
		“Sometimes the lever would move back a little when I open it”
Amount of time to use device
Quick/Just seconds (27/21)	“Takes no time at all to use”	“Less time than any other device”
	“I can’t imagine it being any faster to use”
	“3 to 4 seconds”
	“Only 3 seconds to use, it’s so easy”	“About the same amount of time as my current pump”
		“No one will notice I’m using it, it’s so quick. I’m always on the go and this is a good thing”
		“It’s incredibly quick and fast”
Number of steps (5/6)	“Open, inhale and close”	“Flip, inhale and rinse…you’re done”
	“Just a flip and you breathe it in”	“Just cock it, breathe and go”
Hand feel of the device
Fits hand (17/13)	“I have a small hand and it fits it well”	“Fits in my hand nicely”
	“It’s the right size and shape to fit my hand”	“It has a substantial feel that I like”
Never slipped (12/12)	“Never slipped from my hand”	“It never slipped so I never dropped it”
		“I don’t recall ever dropping it”
	“It doesn’t slip around when you grab it”
		“It never slipped from my hand always felt very secure”
Not too large/compact (11/5)	“It’s compact and not bulky”	“It’s not that big, which is great”
	“It’s not too large, which I like”	“It has a compact size that’s good”
Comfortable to hold (7/3)	“The feel in my hand is comfortable”	“It’s comfortable in my hand”
Easy to hold (6/2)	“It’s got a nice curve to it that makes it nice to hold”	“It has a texture that helps me to hold on to it”
Like grip/design ridges (2/4)	“The ridge marks in the thing help me to hold it”	“It has little grippers that I like, ridges; they really help”
Ease of opening/closing device
Easy (9/14)	“It’s easy to open with one hand”	“It’s obvious what to open and how and there is not much resistance to push it open and closed”
	“Just slides open and closed with little effort”
		“It really takes no strength to slide the cap”
Simple (6/14)	“Just flip it and it’s open, it’s very easy to do”	“Trigger is the cover, it is so easy”
	“It’s just a simple operation, you can even do it with one hand”	“It’s really mistake proof”
		“It’s simple to just pull open. It closes the same way.”
Difficult to slide cover (4/3)	“Sometimes it may stick a little and I need to push a little harder”	“Takes a little pressure to open, was not real smooth”
	“A little harder to open than Advair”	“The lever action was a little gritty from time to time”
No problems (general) (3/3)	“Cover never got stuck, never had a problem”	“No complications, no troubles”
	“There just were no problems”
Grips/ridges/lip (3/3)	“I can slide it over with my thumb. I use the little raised lip to push it over”	“I like the flare ups on the cover, makes it easier to open and close”
Feel of device when placed to the lips
Fits well/seals well (14/17)	“It’s shaped like my lips so I felt I got a good seal”	“It fits well, there is more of it to fit to my lips”
	“Fit my lips perfectly”	“Easy to make a tight seal to be sure inhaling the medicine, and not air.”
	“It seals better than others and I feel I get more of the medicine. I feel I’m getting the full dose.”	“Fit nicely to my lips”
Comfortable (12/9)	“It felt right”	“It was comfortable, I didn’t have to purse my lips”
	“It felt really good to hold it up to my lips”	“Just very comfortable”
	“It felt very comfortable”
Placement of lips (3/2)	“I feel it is a little too small or short, I need to get my mouth around it.”	“The mouthpiece is a little shallow, I put my mouth further up”
Ease of activation
Works even with small breath (14/5)	“Worked even when my breath was shallow”	“I had no problem breathing in the medicine on days I could breathe, it was effortless”
	“It was not hard to draw out the medicine”
	“I didn’t feel I needed to suck as hard”	“I think it takes less breath to get the medicine in”
	“One big inhale and I know I got the medicine”
Easy (4/11)	“Less difficult than an MDI”	“Almost too easy, I called my doctor to make sure I was doing it right”
	“Very easy to inhale”	“It was just real easy to do”
Medicine delivery (7/7)	“I could feel the medicine. I could feel the powder going in”	“I could feel the air flowing through so I knew something was happening”
	“I just felt like I got all the medicine”	“Felt like I could feel the medicine and it was easy to direct it to the back of the mouth”
Not propelled (0/4)		“I would like it better if it was propelled”
		“Don’t feel it the same way as a pump. I have no proof it’s working or dispensing.”
Use and value of dose counter
Big/easy to see/read (17/19)	“I can see the red indicator even without my glasses”	“The black and white numbers are very easy to see”
	“I can read the numbers without my glasses”	“I can see them without my glasses”
	“I don’t need to pull out my magnification to see the numbers”	“The numbers are big and easy to read”
	“It’s large enough I can see it”
Keeps me on track (12/6)	“Indicates to me when doses are getting low”	“Keeps me on track with my medicine”
	“Makes it easier for me to keep up and not forget”	“Helps me know if I took my medicine each day
	“It’s easy to read. It tells me when to refill. And, I know if I took my medicine”	“I like to know if I missed a day, and this helps me
Red indicator (8/7)	“The red indicator tells me I’m close to being out of medicine”	“The red strip tells me when I’m low”
	“9 or less and it goes to red and tells me I’m getting close to being out of medicine”	“I like that it turns red when getting low, I know to reorder.”
	“I like the red indicator”
Helpful (6/6)	“It has actual numbers and that’s helpful, no guessing”	“It’s simply helpful”