Table 3.

Urinary parameters at baseline, before (control), during (intervention) and after administration (follow-up) of the study preparation (n = 20; mean ± standard deviation)

	Baseline	Control	Intervention		Follow-up	P	P	P	P
Diet	Normal-oxalate	Oxalate-rich	Oxalate-rich	Oxalate-rich	Normal-oxalate
Week	Week 0	Week 1	Week 2	Week 6	Week 10	Wk 0 vs. 1	Wk 1 vs. 2	Wk 1 vs. 6	Wk 0 vs. 10
Volume (mL/24 h)	2,379 ± 1,063	2,396 ± 858	2,322 ± 997	2,534 ±1,311	2,433 ± 1,194	0.888	0.550	0.526	0.765
pH	6.38 ± 0.37	6.36 ± 0.31	6.39 ± 0.38	6.39 ± 0.41	6.39 ± 0.21	0.365	0.823	0.667	0.926
Sodium (mmol/24 h)	157 ± 74	182 ± 51	155 ± 65	173 ± 58	179 ± 74	0.100	0.107	0.398	0.204
Potassium (mmol/24 h)	65 ± 29	71 ± 19	82 ± 24	77 ± 28	74 ± 23	0.287	0.044	0.190	0.232
Calcium (mmol/24 h)	4.02 ± 1.83	4.11 ± 1.70	3.85 ± 1.54	4.09 ± 1.51	4.47 ± 2.16	0.881	0.411	0.808	0.334
Magnesium (mmol/24 h)	5.14 ± 2.06	5.18 ± 1.95	4.68 ± 1.75	4.99 ± 1.87	5.56 ± 2.73	0.970	0.262	0.881	0.351
Ammonium (mmol/24 h)	28.1 ± 9.1	26.6 ± 7.2	28.0 ± 8.3	29.8 ± 9.4	30.0 ± 11.8	0.351	0.526	0.218	0.940
Chloride (mmol/24 h)	147 ± 71	178 ± 48	161 ± 68	158 ± 53	182 ± 82	0.026	0.391	0.070	0.052
Phosphate (mmol/24 h)	26.9 ± 8.6	28.2 ± 7.5	28.8 ± 7.7	31.7 ± 10.5	27.4 ± 9.8	0.478	0.681	0.135	0.881
Sulphate (mmol/24 h)	20.5 ± 6.5	20.7 ± 6.7	22.2 ± 5.9	23.4 ± 5.7	20.6 ± 5.2	0.881	0.218	0.161	0.852
Creatinine (mmol/24 h)	12.43 ± 3.50	13.46 ± 4.87	13.19 ± 4.28	13.27 ± 4.22	12.53 ± 3.97	0.232	0.563	0.279	0.940
Uric acid (mmol/24 h)	3.10 ± 0.90	3.27 ± 1.01	3.16 ± 0.74	3.35 ± 0.73	3.16 ± 0.89	0.305	0.681	0.370	0.695
Oxalate (mmol/24 h)	0.354 ± 0.097	0.542 ± 0.163	0.563 ± 0.183	0.638 ±0.197	0.371 ± 0.108	< 0.001	0.563	0.052	0.455
Citrate (mmol/24 h)	3.662 ± 1.567	3.553 ± 1.123	3.640 ± 1.517	3.969 ± 1.461	3.444 ± 1.233	0.526	0.970	0.021	0.279
RS CaOx	3.211 ± 1.672	4.398 ± 2.317	4.867 ± 2.921	5.111 ± 2.973	3.647 ± 2.151	0.004	0.550	0.108	0.332