Table 2.
Global recurrence and local recurrence (LR) following n = 242 primary resections for colorectal liver metastases according to resection margins (RMs)
| |
Resection margins |
||||
|---|---|---|---|---|---|
| Recurrence | A (R1) n (%) | B (1-4 mm) n (%) | C (5-9 mm) n (%) | D (≥10 mm) n (%) | All n (%) |
| LR only |
7 (14.6) |
3 (3.9) |
3 (6.5) |
1 (1.3) |
14 (5.8) |
| LR and hepatic |
3 (6.3) |
3 (3.9) |
3 (6.5) |
1 (1.3) |
10 (4.1) |
| LR and extrahepatic |
6 (12.5) |
10 (13.0) |
0 (0.0) |
0 (0.0) |
16 (6.6) |
| LR (total)1 |
16 (33.3) |
16 (20.7) |
6 (13.0) |
2 (2.8) |
40 (16.5) |
| Hepatic only |
8 (16.7) |
15 (19.5) |
7 (15.2) |
22 (31.0) |
52 (21.5) |
| Extrahepatic |
13 (27.1) |
31 (40.3) |
17 (37.0) |
18 (25.4) |
79 (32.6) |
| Unknown |
2 (4.2) |
1 (1.3) |
0 (0.0) |
1 (1.3) |
4 (1.7) |
| Global2 |
39 (81.3) |
63 (81.8) |
30 (65.2) |
43 (60.5) |
175 (72.3) |
| No recurrence |
9 (18.8) |
14 (18.2) |
16 (34.8) |
28 (39.4) |
67 (27.7) |
| Total | 48 (100) | 77 (100) | 46 (100) | 71 (100) | 242 (100) |
Extrahepatic recurrence: recurrence outside the liver with or without hepatic involvement. Statistics: P = 0.0003 (χ2 two-sided exact test) when all groups were included.
1LR (total): the sum of ‘LR only’, ‘LR and hepatic’ and ‘LR and extrahepatic’.
2Global recurrence: the sum of ‘LR (total)’, ‘hepatic only’, ‘extrahepatic’, and ‘unknown recurrence’.