Table 2.
Univariate and multivariate regression analysis for relapse-free survival (RFS) of stage III colon cancer
| Variable | Comparison |
Univariate |
Multivariate |
||
|---|---|---|---|---|---|
| P value | HR | 95% CI | P value | ||
| Gender |
Female versus male |
0.24 |
|
|
|
| Age |
|
0.001 |
1.01 |
0.986 to 1.043 |
0.324 |
| Comorbidity |
No versus yes |
0.745 |
|
|
|
| ASA (grade ≥3) |
No versus yes |
0.008 |
1.000 |
0.505 to 1.98 |
0.999 |
| Location |
Right versus left side of colon |
0.306 |
|
|
|
| |
Colon versus rectosigmoid |
0.406 |
|
|
|
| Serum CEA |
<5 versus ≥5 |
0.074 |
0.84 |
0.519 to 1.366 |
0.49 |
| Operation |
Laparoscopic versus open surgery |
0.082 |
1.01 |
0.597 to 1.700 |
0.98 |
| Tumor depth |
T1, 2 versus T3, 4 |
0.002 |
0.26 |
0.089 to 0.733 |
0.01 |
| Lymph node metastasis |
N1 (1 to 3) versus N2 (4<) |
0.004 |
0.71 |
0.387 to 1.301 |
0.27 |
| TNM stage |
IIIA, B versus IIIC |
<0.0001 |
0.4 |
0.204 to 0.797 |
0.01 |
| Adjuvant chemotherapy | No versus yes | <0.0001 | 2.65 | 1.48 to 4.756 | 0.001 |
ASA, American Society of Anesthesiologists physical status classification system; CEA, carcinoembryonic antigen; CI, confidence interval; HR, hazard ratio; TNM, tumor, node, metastasis.