Table 2.
HRQOL and treatment satisfaction
| Start 2006 study (A) | End SC phase (B) | End CIPII phase (C) | 2012 study (D) | D vs. A | D vs. B | D vs. C | |
|---|---|---|---|---|---|---|---|
|
SF-36 subscales |
|
|
|
|
|
|
|
| Physical functioning |
76 (66, 86) |
69 (59, 79) |
81 (71, 91) |
76 (65, 86) |
-0.3 (-19.7, 19.1) |
7.4 (-12.1, 26.8) |
-5.3 (-24.7, 14.1) |
| Social functioning |
68 (53, 76) |
65 (53, 76) |
77 (66, 88) |
74 (63, 85) |
6.6 (-14.7, 27.8) |
9.9 (-11.4, 31.2) |
-2.6 (-32.9, 18.6) |
| Role limitations-physical |
38 (17, 59) |
42 (21, 63) |
66 (45, 87) |
57 (36, 78) |
18.4 (-22.0, 58.8) |
14.5 (-26.0, 54.9) |
-9.2 (-49.6, 31.2) |
| Role limitations-emotional |
68 (50, 87) |
68 (50, 87) |
86 (67, 100) |
77 (58, 96) |
8.8 (-27.3, 44.8) |
8.8 (-27.3, 44.8) |
-8.8 (-44.8, 27.3) |
| Mental health |
70 (60, 79) |
67 (58, 77) |
77 (68, 87) |
79 (70, 89) |
9.6 (-8.1, 27.4) |
12.0 (-5.8, 29.7) |
2.1 (-15.7, 19.8) |
| Vitality |
48 (39, 58) |
43 (34, 71) |
62 (52, 71) |
58 (49, 67) |
9.5 (-7.9, 26.9) |
15.3 (-2.2, 32.7) |
-4.5 (-32.9, 12.8) |
| Bodily pain |
64 (52, 75) |
64 (53, 76) |
66 (54, 77) |
67 (56, 78) |
3.3 (-18.5, 25.0) |
2.6 (-19.2, 24.3) |
1.4 (-20.4, 23.1) |
| General health |
41 (32, 50) |
46 (37, 54) |
56 (47, 64) |
48 (38, 56) |
6.5 (-10.1, 23.1) |
1.7 (-14.9, 18.3) |
-8.0 (-24.7, 8.6) |
|
SF-36 summary scores |
|
|
|
|
|
|
|
| Physical component score |
56 (46, 65) |
55 (45, 64) |
68 (58, 77) |
63 (54, 73) |
7.3 (-10.9, 25.6) |
8.5 (-9.7, 26.8) |
-4.7 (-23.0, 13.5) |
| Mental component score |
59 (50, 68) |
58 (49, 67) |
72 (63, 81) |
67 (58, 76) |
8.2 (-9.1, 25.5) |
9.5 (-7.7, 26.8) |
-4.4 (-21.6, 12.9) |
|
WHO-5 score |
49 (39, 59) |
47 (37, 57) |
69 (59, 79) |
60 (50, 70) |
10.5 (-9.0, 30.0) |
12.6 (-6.9, 32.1) |
-9.2 (-28.8, 10.2) |
|
DTSQ |
|
|
|
|
|
|
|
| Total score |
24 (21, 27) |
24 (21, 27) |
33 (30, 36) |
33 (29, 36) |
8.3 (2.3, 14.3)* |
8.4 (2.4,14.3)* |
-0.3 (-6.3, 5.7) |
| Perceived hypoglycaemia score |
5 (4, 6) |
5 (4, 5) |
2 (2, 3) |
4 (3, 5) |
-0.4 (-2.0, 1.2) |
-0.8 (-2.4, 0.8) |
0.3 (-1.3, 1.9) |
| Perceived hyperglycaemia score | 3 (2, 4) | 4 (3, 5) | 3 (2, 3) | 3 (2, 4) | -1.1 (-2.4, 0.1) | -0.9 (-2.1, 0.3) | 1.5 (0.2, 2.7)* |
Estimated values and differences are reported. Data are presented as estimated mean (95% CI) or mean change (95% CI). Numbers may not add up due to rounding. DTSQ; Diabetes Treatment Satisfaction Questionnaire, CIPII; continuous intraperitoneal insulin infusion, SC; subcutaneous, SF-36; 36-item short-form health survey, WHO-5; World Health Organization-Five Well-Being Index *p < 0.05.