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. 2014 Apr 24;33(1):34. doi: 10.1186/1756-9966-33-34

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Copyright © 2014 Yue et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Shh/Gli signaling down-regulates E-Cadherin expression. Immunofluorescent staining of E-Cad (green) in lung SCC H2170 cells treated with Gli-I, vismodegib, and recombinant Shh proteins. DAPI (blue) was used to stain nuclei of those cells.