Table 3.
Left Ventricular Echocardiographic Profile from Time of Cardiomyopathy Diagnosis to 2 Years, by Echocardiographic Status or Clinical Outcome within 2 Years after Diagnosis. Mean and standard deviation are shown.
| Status at 2 years Post-Diagnosis
| ||||||
|---|---|---|---|---|---|---|
| Echo Characteristic |
Normalized | Death or Transplant | Persistently Abnormal | |||
|
| ||||||
| At Diagnosis, n=96 |
Follow-up Echocardiogram* n=96 |
At Diagnosis, n=317 |
Follow-up Echocardiogram* n=202 |
At Diagnosis, n=328 |
Follow-up Echocardiogram* n=328 |
|
| EDD, z-score | 4.56 (1.87) | −0.06 (4.25) | 5.70 (2.06) | 6.05 (2.34) | 5.41 (2.06) | 3.43 (2.63) |
| ESD, z-score | 6.39 (2.03) | −0.17 (3.56) | 7.69 (1.95) | 7.79 (2.37) | 7.20 (2.09) | 4.40 (3.06) |
| FS, z-score | −9.21 (2.86) | −0.08 (1.74) | −10.28 (2.28) | −9.79 (3.14) | −9.34 (2.81) | −5.49 (3.67) |
| FS, % | 15.40 (6.88) | 37.12 (4.76) | 11.44 (4.92) | 12.60 (7.19) | 14.65 (6.33) | 23.16 (9.14) |
| PWT, z-score | −0.16 (2.29) | −0.58 (1.84) | −0.39 (2.57) | 0.15 (2.29) | −0.45 (2.56) | −0.74 (2.64) |
| SWT, z-score | −0.77 (1.46) | −0.53 (1.40) | −0.94 (1.73) | −0.75 (1.49) | −0.88 (1.88) | −0.81 (1.90) |
| Mass, z-score | 2.71 (1.85) | −0.35 (1.83) | 3.42 (2.53) | 3.89 (2.44) | 3.11 (2.23) | 1.55 (2.60) |
| PWT:EDD | 0.13 (0.04) | 0.18 (0.13) | 0.12 (0.07) | 0.13 (0.05) | 0.12 (0.04) | 0.14 (0.08) |
| PWT:EDD, z-score | −1.80 (1.48) | −0.26 (4.66) | −2.23 (2.31) | −1.94 (1.88) | −2.17 (1.48 | −1.62 (2.63) |
EDD, end diastolic dimension; ESD, end systolic dimension; FS, fractional shortening; PWT, posterior wall thickness; SWT, septal wall thickness
*
Follow-up echocardiogram defined as: the first occurrence of normalization for the Normalized group; the latest echocardiogram before death/transplant for the Death/Transplant group; and the latest echocardiogram within 2 years following diagnosis for the Persistently Abnormal group.