Fig. 4.

FGFI signatures for characterization of MCI when the size of the clique is 3. a The PFSs of the clustered cliques. Green and red stand for lower and higher PFSs, respectively. We identified 58 cliques showing consistently increased PFS and 39 cliques showing consistently decreased PFS in MCI group, compared with the normal control group. The vertical white dashed line separates MCI and controls, while the horizontal dashed white line separates significantly increases and decreased functional interactions in MCI. The spatial distributions of these cliques on the cortical surface are shown in b for increased PFSs and c for decreased PFSs. In (b) and (c), the DICCCOL landmarks are represented as spheres. Green ones are those landmarks involved in the cliques showing significantly altered PFSs