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. 2014 May 13;14:332. doi: 10.1186/1471-2407-14-332

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Copyright © 2014 Hartmann et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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“LP type” DLBCL, presumably transformed from NLPHL. Cervical lymph node biopsy of one of the patients presenting with “LP type” DLBCL. a. HE, 40×. The lymph node architecture is effaced with open sinuses. b. HE, 400×. Higher magnification reveals a blast infiltrate with a broad, pale cytoplasm and large numbers of histiocytes. c. Blasts stain partly positive for CD75 (400×). d. A subset of blasts is positive for J-chain (400×). e. The infiltrate weakly expresses EMA (200×). f. IgD is strongly expressed in the blast population (400×).