Table 1.
Summary of patient characteristics, including sites of metastatic disease
| Melanoma (%) N=314 | Renal cell carcinoma (%) N=186 | |
|---|---|---|
|
Gender |
|
|
| Male |
187 (60) |
138 (74) |
| Female |
127 (40) |
48 (26) |
|
Age |
|
|
| Mean (SD) |
53.2 (11.9) |
57.3 (9.1) |
| Range |
20 -79 |
30 – 80 |
|
ECOG performance status |
|
|
| 0 |
220 (71) |
136 (73) |
| 1 |
85 (27) |
47 (25) |
| 2 |
7 (2) |
3 (2) |
|
Sites of metastatic disease |
|
|
| Lymph node |
154 (49) |
39 (21) |
| Lung |
181 (58) |
137 (74) |
| Liver |
96 (31) |
31 (17) |
| Bone |
79 (25) |
43 (23) |
| Brain |
47 (15) |
14 (7) |
| Subcutaneous |
69 (22) |
1(1) |
|
Number of metastatic sites |
|
|
| 1 |
42 (13) |
61 (33) |
| 2 |
69 (22) |
50 (27) |
| 3 |
54 (17) |
38 (20) |
| 4 |
149 (48) |
37 (20) |
|
Prior treatment |
|
|
| Nephrectomy |
2 (1) |
162 (87) |
| Radiation |
139 (44) |
41 (22) |
| Chemotherapy |
28 (9) |
8 (4) |
| Immunotherapy |
119 (38) |
9 (5) |
| VEGF TKI |
0 (0) |
11 (6) |
| Other | 71 (23) | 24 (13) |