Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 5;11:71. doi: 10.1186/1742-2094-11-71

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Li et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

PD168393 inhibited EGFR phosphorylation of astrocytes in an in vitro scratch wound model. Cultured astrocytes were immunostained for pEGFR, GFAP and DAPI in control (A1-A4), injury, (B1-B4) and PD168393 (40 μM) treatment groups (C1-C4) at 24 hours after injury (n = 5 in each group). (A1-C1) immunolabeling for pEFGR, (A2-C2), GFAP, (A3-C3) DAPI and (A4-C4) for co-localization of pEGFR, GFAP and DAPI. Scale bars = 100 μm. Representative Western blots of pEGFR and GFAP expression are shown (n = 3/group) (D). Semiquantitative analysis of pEGFR as a ratio of EGFR loading and semiquantitative measurements of GFAP were obtained by normalization to β-actin (E). *P < 0.05.