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Disrupted in schizophrenia 1 (DISC1) knockdown (KD) virus reduced DISC1 expression in the prefrontal cortex (PFC) in DISC1 KD rats. Length density of DISC1-labeled dendrites was measured in PFC using stereology and normalized to that in motor cortex. The length density in PFC was reduced in the DISC1 KD group relative to that in the Control (Con; *P=0.003), Scrambled (Scr; *P=0.001), and Anatomical Control (Anat Con; *P=0.001) groups.
