Table I.

Characteristics of patients with severe, mild to moderate and no cardiac siderosis at baseline.

Characteristic	Severe cardiac siderosis (n=13)	Mild-moderate cardiac siderosis (n=8)	No cardiac siderosis (n=33)	p-value
Mean Age (yrs) (range)	34.7(21-61)	39.3(27-50)	31.3(11-54)	0.28
Gender (Male:Female)	3:10	3:5	12:21	0.70
Mean transfusion burden (ml/kg/yr)±SD	128.1±14.2	114.8±14.7	120.3±45.6	0.815
Median baseline ferritin (mg/dl) (range)	1759(388-17489)	1254(523-2661)	1026 (342-3322)	0.418
Mean baseline cardiac T2* (msec)±SD	6.9±1.6	14.6±2.9	36.3±7.3	<0.0001
Median baseline LIC (mg Fe/gm dry weight) (range)	4.3(0.4-46)	2.2(1.2-16)	3.3(0.4-32)	0.523
Mean LVEF (%)±SD	56.3±10.1	60±5	66±8.2	0.003

LIC- liver iron concentration, LVEF- left ventricular ejection fraction

LIC was calculated from liver T2* value measured by MRI