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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2013 Jul 5;12(9):1774–1782. doi: 10.1158/1535-7163.MCT-12-1023

Figure 4.

Figure 4

In these experiments cells were exposed to a concentration of immunotoxin for 12 hours and a concentration of potentiator for 24 hours with potentiator exposure starting at either the same time (t= 0) or delayed by 12, 24, or 48 hours. (a) A431 cells treated with E4rGel immunotoxin and E6LLO potentiator, both non-competitively targeting EGFR. (b) HT-29 cells treated with C7rGel immunotoxin targeting CEA and E6LLO potentiator targeting EGFR. We observe that potentiators can be effective even after a 48 hour delay in treatments depending on concentration.