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. Author manuscript; available in PMC: 2014 May 22.

Published in final edited form as: Otol Neurotol. 2010 Sep;31(7):1135–1143. doi: 10.1097/MAO.0b013e3181eb328a

Change in word recognition after treatment using erlotinib 150 mg daily. The vertical line indicates the start of treatment (day 0). Patients who did not undergo audiologic evaluation (n=1) and those with surgical resection of both auditory nerves (n=1) were excluded from analysis. One patient was tested only with pure tone audiometry. (a) Stable word recognition scores were documented in five patients during treatment. (b) Progressive hearing loss was documented in 3 patients, including one patient with transient hearing improvement. * indicate timepoints qualifying as a hearing response. (c) Time to progressive hearing loss in 7 evaluable patients.

Change in word recognition after treatment using erlotinib 150 mg daily. The vertical line indicates the start of treatment (day 0). Patients who did not undergo audiologic evaluation (n=1) and those with surgical resection of both auditory nerves (n=1) were excluded from analysis. One patient was tested only with pure tone audiometry. (a) Stable word recognition scores were documented in five patients during treatment. (b) Progressive hearing loss was documented in 3 patients, including one patient with transient hearing improvement. * indicate timepoints qualifying as a hearing response. (c) Time to progressive hearing loss in 7 evaluable patients.