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. Author manuscript; available in PMC: 2014 May 22.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Apr 24;246(0):58–65. doi: 10.1016/j.taap.2010.04.006

Figure 4.

Figure 4

72 hr dose response evaluation using manual QRTPCR. The x-axis indicates the dose of TCDD, the y-axis represents the fold change calculated relative to time-matched vehicle controls (n=5). Curves were generated in GraphPad Prism 4.0 using non-linear regression; ED50 values were obtained using an automated dose-response modeler (Burgoon and Zacharewski, 2008). The asterisk (*) indicates significant fold induction by TCDD relative to vehicle controls at p < 0.05