Table 3.
Time point (hrs) |
Number of Differentially Regulated Genes |
Primary Complex Altered | Genes Meeting Cut-offs |
---|---|---|---|
2 | 10 | Complex I | Ndufal 1, Ndufa3, Ndufa4, Ndufafl, Ndufb6, Ndufs3, Cox5b, Cox6b1, Atpaf1, Atp5d |
4 | 10 | Complex I | Ndufa4, Ndufb10, Ndufb7, Ndufs1, Ndufs2, Ndufv3, Uqcrc2, Uqcrq, Cox6c, Ucp2 |
8 | 7 | Complex I and V | Ndufa8, Ndufb6, Ndufs2, Cox6a2, Atp5b, Atp5f1, Atp5j |
12 | 4 | Complex I | Ndufa3, Ndufv2, Rieske, Atpaf2 |
18 | 12 | Complex I | Ndufa12, Ndufa5, Ndufa6, Ndufs3, Ndufv2, Ndufv3, Ucrc, Uqcrb, Uqcrq, Cox6a2, Atp5l, Sco1 |
24 | 10 | Complex I | Ndufa10, Ndufa11, Ndufa12, Ndufa3, Ndufa4, Ndufb3, Ndufb6, Ndufc2, Uqcrc2, Atpaf1 |
72 | 11 | Complex IV | Ndufa7, Ndufs8, Cyc1, Uqcr, Uqcrc2, Cox4i1, Cox6b1, Cox7a2, Cox7b, Atp5g2, Atp5g3 |
168 | 17 | Complex I | Ndufa10, Ndufa12l, Ndufa2, Ndufa4l2, Ndufa8, Ndufb11, Ndufb2, Ndufs1, Ndufs3, Uqcrc1, Cox4i2, Cox6b1, Cox6c, Atp5b, Atp5f1, Atp5l, Ucp4 |
Note: genes included meet statistical (P-value < 0.1) and fold change (fold change| > 1.5) cut-offs. Primary complex altered indicates the complex most represented at that time point.