. 2014 May 13;5(3):e00894-14. doi: 10.1128/mBio.00894-14

TABLE 2 .

Genetic characteristics of LRCoNS (n = 28)

Case	Species	ST	cfr	cfr plasmid	% of 23S rRNA copies harboring SNV				L3 mutation(s)	L4 mutation	Linezolid MIC (µg/ml)^a
Case	Species	ST	cfr	cfr plasmid	G2576U	C2534U	G2447U	U2504A	L3 mutation(s)	L4 mutation	Linezolid MIC (µg/ml)^a
1	S. epidermidis	5			0	20	0	0	H146Q, V154L, A157R	71 N	128
2		5	Present	Small^b	0	20	0	0	H146Q, V154L, A157R	71 N	256
3		5	Present	Small	0	20	0	0	H146Q, V154L, A157R	71 N	>256
4		5			0	20	0	0	H146Q, V154L, A157R	71 N	32
6		23	Present	Large^c	0	0	0	0	D159L		128
7		23			0	0	0	0	D159L	K68N	16
19		23			100	100	0	0			32
20		23	Present	Large	0	0	0	0	D159L		128
5		23			0	0	0	0	D159L		8
13		23	Present	Large	0	0	0	0	D159L		8
18		23	Present	Large	0	0	0	0	D159L		32
28		23	Present	Large	0	0	0	0	D159L		128
22		23			100	0	0	0			16
14		24	Present	Small	0	40	0	0	H146Q, V154L, A157R	71 N	>256
15		185			0	0	100	0	A157R		>256
27		186			0	40	0	0	H146Q, V154L, A157R	71 N	32
23		186	Present	Small	0	40	0	0	V154L, A157R	71 N	>256
17		186			0	40	0	0	H146Q, V154L, A157R	71 N	32
25		186	Present	Small	0	40	0	0	H146Q, V154L, A157R	71 N	>256
26		186			0	40	0	0	H146Q, V154L, A157R	71 N	64
21		186-like			0	40	0	0	H146Q, V154L, A157R	71 N	32
8	S. haemolyticus				100	100	100	100			64
10					100	100	100	100			64
24					100	100	100	100			64
11					100	100	100	100			64
12					100	100	100	100			128
16					100	100	100	100	G139R		64
9					100	100	100	100			64

^{^a}

Determined by broth microdilution.

^{^b}

Small (2.8- to 3.8-kb) plasmid with homology to the cfr-carrying plasmid identified in Staphylococcus cohnii (14).

^{^c}

Large (17-kb) plasmid with 70% homology to the cfr-carrying plasmid pSCFS1, identified in Staphylococcus sciuri (13).