Figure 4.
Silencing of AKR1B10 dynamic expression using a shRNA approach. Western blot demonstrates markedly decreased expression of AKR1B10 in 2 separate Hu7 knockdown clones (#1 and #2, respectively) (A) with concomitant decrease in colony size and formation that parallels AKR1B10 expression (B and C; *p<0.05).