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. Author manuscript; available in PMC: 2014 Jul 5.
Published in final edited form as: Cancer Genet. 2013 Jul 5;206(5):191–205. doi: 10.1016/j.cancergen.2013.04.006

Table 4. Integration of SKY and aCGH data for chromosome 9 rearrangements leading to HD in 9p21.3 region in malignant mesothelioma cell lines.

Cell line Ploidy 9p losses by CGH 9p rearrangements by SKY Events leading to HD Cartoon
H2869 2n− Homozygous microdeletion 9p21.3 9×2 Microdeletion on one copy of chr9, loss of normal chr9, and gain of second copy of chr9 with microdeletion A
H2373 2n− Homozygous deletion 9p21.2-21.3 Del(9)(p21.2-p21.3)×2 Deletion on one copy of chr9, loss of normal chr9, and gain of second copy of chr9 with deletion A
H2795 2n± Homozygous deletion 9p21.1-p21.3 del(9)(p21.1-p21.3)×2 Deletion on one copy of chr9, loss of normal chr9, and gain of second copy of chr9 with deletion A
H2818 2n− Homozygous deletion on 9p21.3, loss of 9p 9, der(5)del(5)(q14q23)t(5;9)(p14;q21) Microdeletion on one copy of chr9, loss of 9q21-pter due to unbalanced translocation B
H2461 2n− Homozygous microdeletion on 9p21.3, loss of 9p 9, der(15)t(9;15)(q12;p13) Microdeletion on one copy of chr9, loss of 9q12-pter due to unbalanced translocation B
H513 3n− homozygous microdeletion on 9p21.3, loss of 9p21.2-pter 9, der(9)t(9;13)×2 Microdeletion on one copy of chr9, loss of 9p21.2-pter due to unbalanced translocation, and gain of the second copy of der(9) C (or E)
H2731 2n+ Homozygous deletion on 9p21.3 i(9)(p10), del(9)(p11), der(9;11) (q10;q10)×2 Microdeletion on one copy of chr9, loss of second copy of 9p due to unbalanced translocation,isochromosome i(9)(p10) formation, and gain of the second copy der(9;11) C (or E)
H28 3n±/4n− Homozygous microdeletion on 9p21.3, loss of 9p13.3-pter 9x2, der(9)t(9;17)(p13;q21)×2 Microdeletion on one copy of chr9, loss of 9p13.3 due to unbalanced translocation, and tetraploidization D
H2369 3n+/4n− Homozygous microdeletion on 9p21.3, loss of 9p11-pter 9x2, der(5;9)(p10;q10)×2 Microdeletion on one copy of chr9, loss of 9p due to unbalanced translocation, and tetraploidization D
H2722 3n+ Homozygous deletion 9p21.1-p21.3, loss of 9p11-pter del(9)(p21.1-p21.3), der(15)t(9;15) (q11;q14)×2 Deletion on one copy of chr9, loss of second 9p due to unbalanced translocation, tetraploidization, and loss one copy of del(9) E
H290 3n+/5n− homozygous deletion 9p21.1-p21.3, loss of 9p21.1-pter, gain of 9p13.3-p21.1 9x(2-5 copies), der(5)t(5;9)(?; p21.1) ×(0-3copies) Deletion 9p21.1-p21.3, loss of 9p13-pter due to unbalanced translocation, tetraploidization, further gains and losses, and structural rearrangements E,F
H2810 3n±/4n± Homozygous deletion 9p21.3, loss of 9p24.1-pter 9×2, der(9)t(9;22)(p13;?), der(9)t(9;15) (p24.1;?), der(9)t(7;9)(?;p24.1) Deletion 9p21.1-p21.3, loss of 9p13-pter due to unbalanced translocation, tetraploidization, further gains and losses, and structural rearrangements E,F