Table III.
Results of vaginal cultures and fertility studies.
Experimental groups | # of mice shed/ Total # mice (% +) | Total # IFU shed/mouse median (range) | Length of shedding Median days (range) | # of fertile mice/ Total # mice (% +) | mouse (mean ± 1SD) |
---|---|---|---|---|---|
|
|
|
|
|
|
nMOMP/Z3-14 | 12/15a (80) | 147,031c,d,e (<2–1,921,070) | 21d,e (4–35) | 12/15h,i (80) | 4.87±3.56c,k,l |
nMOMP/A8-35 | 11/16b,h (69) | 14,125d,e,f (<2–2,817,998) | 12d,e,f,g (4–21) | 12/16b,h ,i(75) | 3.75±2.86f,k ,l |
OVA/Z3-14 | 12/12 (100) | 2,719,510 (272,555–9,862,992) | 25 (14–35) | 7/12a (58) | 2.00±1.91d,m |
OVA/A8-35 | 13/13 (100) | 1,886,340 (1,159,330–4,800,672) | 28 (14–35) | 4/13a,j (31) | 1.31±2.18d,m |
MEM-0 | 8/8 (100) | 9,059,562 (894,734–13,003,396) | 32 (21–35) | 4/7 (57) | 1.86±2.04 |
Cm-EB | 4/14 (29) | <2 (<2–38,315) | 4 (4–14) | 14/14 (100) | 6.07±2.16 |
Fertility control | - | - | 14/16 (88) | 4.44±2.76 |
P<0.05 by the Fisher’s Exact test compared to the Cm-EB immunized group.
P<0.05 by the Fisher’s Exact test compared to the OVA/A8-35 immunized group.
P<0.05 by Mann-Whitney Rank Sum Test compared to OVA/Z3-14 immunized group.
P<0.05 by Mann-Whitney Rank Sum Test compared to Cm-EB immunized group.
P<0.05 by Mann-Whitney Rank Sum Test compared to MEM-0 immunized group.
P<0.05 by Mann-Whitney Rank Sum Test compared to OVA/A8-35 immunized group.
P<0.05 by Mann-Whitney Rank Sum Test compared to nMOMP/Z3-14 immunized group.
P>0.05 by the Fisher’s Exact test compared to the Cm-EB immunized group.
P>0.05 by the Fisher’s Exact test compared to the Fertility control group.
P<0.05 by the Fisher’s Exact test compared to the Fertility control group.
P>0.05 by the Mann-Whitney Rank Sum Test compared to the Cm-EB immunized group.
P>0.05 by the Mann-Whitney Rank Sum Test compared to the Fertility control group.
P<0.05 by the Mann-Whitney Rank Sum Test compared to the Fertility control group.