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Analysis of covariance with 2 factors (group, race) and one covariate (glomerular filtration rate).
| Category | Genotype | Adjusted Means of Homocysteine | p* |
| Caucasian controls | MTHFR 677 CC | 7.7 | — |
| CT | 9.4 | 0.0196 | |
| TT | 9.8 | 0.0275 | |
| Caucasian controls | MTHFR 1298 AA | 9.6 | — |
| AC/CC† | 7.8 | 0.0083 |
p value for comparison to wild-type genotype.
These genotypes were combined because of low numbers of homozygotes.
