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Curcumin loaded magnetic nanoparticle (MNP-CUR) formulation targets tumor cells in HPAF-II xenograft mouse model. (A) Schematic representation of possible targeting behavior of curcumin NPs to tumor cells. (B) MNP-CUR internalization in tumor cells in vivo. MNP-CUR (20 µg per mice) was administered via intraperitoneal injection and internalization in tumor cells was detected with Prussian blue staining. Black arrows indicate MNP-CUR NPs internalization in tumor cells.
