Table 1a.
Stratified analyses.
| Studies | Participants | RR (95% CI) | Studies | Participants | RR (95% CI) | |
|---|---|---|---|---|---|---|
| Quality Measure | Adequate | Inadequate | ||||
| Description of randomization | 38 | 202,150 | 1.00 (0.98,1.03) | 18 | 44,193 | 0.96 (0.90,1.02) |
| Description of blinding method | 34 | 170,610 | 1.01 (0.99,1.03) | 22 | 75,733 | 0.98 (0.94,1.02) |
| Baseline Mortality Risk | Above | Below | ||||
| Control arm death rate vs. median | 29 | 139,598 | 1.00 (0.97,1.03) | 28 | 106,773 | 0.99 (0.93,1.06) |
| Dose (IU/d) | Less than | Greater than or equal to | ||||
| 100 | 10 | 77,931 | 0.97 (0.93,1.02) | 47 | 168,440 | 1.01 (0.98,1.04) |
| 400 | 20 | 147,215 | 0.99 (0.97,1.02) | 37 | 99,156 | 1.02 (0.97,1.06) |
| 500 | 32 | 215,601 | 1.00 (0.98,1.02) | 25 | 30,770 | 1.03 (0.95, .11) |
| 800 | 45 | 242,971 | 1.00 (0.98,1.02) | 12 | 3,400 | 1.04 (0.91,1.20) |
| Age | Included | Excluded | ||||
| Subjects under age 55 | 35 | 221,662 | 1.00 (0.98,1.02) | 16 | 23,583 | 1.01 (0.92,1.10) |
| Subjects under age 60 | 50 | 243,243 | 1.00 (0.98,1.02) | 7 | 3,128 | 0.94 (0.78,1.13) |
| Vitamin E Type | Natural Source | Synthetic | ||||
| 16 | 64,648 | 1.02 (0.96,1.08) | 16 | 174,859 | 1.01 (0.92,1.10) | |