Figure 4.

Whole bone mechanical performance comparison of BT^KO and wild-type femora. Three-point bending analysis was performed on femora from 10 BT^KO and 13 control males, and from 10 each BT^KO and control females. Both femora from each animal were tested, and the averaged value taken as the femoral biomechanical performance for that mouse. P-values: *< 0.05, **< 0.01, ***< 0.001. Representative load-displacement curves for control and BT^KO femora are shown. Yield points mark the beginnings of plastic deformation of bones.