Table 6. In Vitro Inhibition of HDACs Isoforms of 11r^a.

classes of HDACs	isoforms	IC50	fold selective for HDAC3	fold selective for HDAC1
class II	HDAC1	11.8
	HDAC2	498.1	127.7	42.2
	HDAC3	3.9
	HDAC8	2000.8	513.0	169.6
class IIa	HDAC4	5700.7	1461.7	483.1
class IIb	HDAC6	308.2	79.0	26.1
class IV	HDAC11	900.4	230.9	76.3

^aAssays were performed in replicate (n ≥ 2); the SD values are <20% of the mean.